{"text_format":"3","workbook":"xls","n_sheets":3,"sheets":["Foglio1","Foglio2","Foglio3"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Foglio1","index":0,"n_rows":59,"n_cols":10,"rows_kept":59,"flags":["formulas_cached_only"]}
[{"$nulls":5},"    Universita degli Studi di Perugia"]
[{"$nulls":5}," Sezione di Chirurgia Oncologica della Mammella e dei Tesuti Molli"]
[{"$nulls":5},"Dir.: Prof. Antonio Rulli"]
[{"$nulls":5}," Biopsia Liquida Early Breast Cancer"]
[null,"N°","Code","Data prel.","N.C.","Data nas.","Età","Istol.","1°CTC ","2°CTC "]
[null,1,"0000/A","2018-04-11","G.M.","1975-05-06","aa.43","sano",0]
[null,2,"0021/A","2018-06-20","P.V.","1941-05-04","aa.77","sano",0]
[null,3,"0035/A","2018-07-30","R.L.","1947-06-13","aa.71","sano",0]
[]
[null,4,"0009/A","2018-05-16","G.R.","1977-03-15","aa.41","in situ",3,3]
[null,5,"0015/A","2018-05-30","B.I.","1956-03-04","aa.62","in situ",0,0]
[null,6,"0031/A","2018-07-23","P.R.","1955-01-01","aa.63","in situ",1,0]
[]
[null,7,"0000/A","2017-10-02","T.M.","1986-02-09","aa.32","cr.infil."]
[null,8,"0024/A","2018-07-02","P.C.","1957-07-10","aa.61","cr.infil."]
[null,9,"0025/A","2018-07-02","B.A.R.","1958-05-18","aa.60","cr.infil."]
[]
[null,10,"0001/A","2018-04-11","C.N.","1958-06-06","aa.60","cr.infil.",1,"†"]
[null,11,"0002/A","2018-04-11","M.L.","1957-09-30","aa.61","cr.infil.",4,"†"]
[]
[null,12,"0003/A","2018-05-09","T.V.","1968-01-01","aa.50","cr.infil.",1,1]
[null,13,"0004/A","2018-05-09","G. M.Cl.","1959-06-10","aa.59","cr.infil.",2,0]
[null,14,"0005/A","2018-05-09","P.B.S.","1978-11-30","aa.40","cr.infil.",6,1]
[null,15,"0006/A","2018-05-09","F.S.","1979-08-03","aa.39","cr.infil.",7,4]
[null,16,"0007/A","2018-05-14","P.V.","1956-06-01","aa.62","cr.infil.",1,0]
[null,17,"0008/A","2018-05-14","Ch.Z.","1957-04-30","aa.61","cr.infil.",28,0]
[null,18,"0010/A","2018-05-16","A.A.","1971-07-26","aa.47","cr.infil.",3]
[null,19,"0011/A","2018-05-21","B.M.","1959-07-14","aa.59","cr.infil.",1,0]
[null,20,"0012/A","2018-05-21","P.D.","1957-03-30","aa.61","cr.infil.",1,7]
[null,21,"0013/A","2018-05-28","A.A.","1985-10-20","aa.33","cr.infil.",10,1]
[null,22,"0014/A","2018-05-28","B.G.","1984-06-02","aa.34","cr.infil.",7,0]
[null,23,"0016/A","2018-05-30","Ch.I.","1954-06-04","aa.64","cr.infil.",1,2]
[null,24,"0017/A","2018-06-06","P.P.","1959-04-02","aa.59","cr.infil.",3,3]
[null,25,"0018/A","2018-06-06","M.G.","1947-06-06","aa.71","cr.infil.",3,3]
[null,26,"0019/A","2018-06-13","C.S.","1949-08-12","aa.69","cr.infil.",0,1]
[null,27,"0020/A","2018-06-13","C.S.","1971-01-15","aa.47","cr.infil.",1,0]
[null,28,"0022/A","2018-06-20","M.S.","1962-10-26","aa.56","cr.infil.",2,4]
[null,29,"0023/A","2018-06-25","P.G.","1964-01-22","aa.54","lob.infil.",0,0]
[null,30,"0026/A","2018-07-10","M.M.","1960-01-14","aa.58","cr.infil.",3,2]
[null,31,"0028/A","2018-07-16","C.S.","1967-12-30","aa.51","cr.infil.",1,0]
[null,32,"0029/A","2018-07-16","F.A.","1959-07-22","aa.59","cr.infil.",7,3]
[null,33,"0030/A","2018-07-18","B.N.","1971-06-23","aa.47","cr.infil.",0,4]
[null,34,"0032/A","2018-07-23","Y.A.","1973-12-31","aa.45","cr.infil.",0,1]
[null,35,"0033/A","2018-07-24","A.Ch.","1957-09-29","aa.61","cr.infil.",1,0]
[null,36,"0034/A","2018-07-24","P.G.","1948-04-12","aa.70","cr.infil.",1,0]
[null,37,"0036/A","2018-08-06","M.R.","1970-09-07","aa.48","cr.infil.",5,3]
[null,38,"0037/A","2018-08-06","V.A.G.","1951-07-25","aa.67","cr.infil.",4,0]
[null,39,"0038/A","2018-11-05","C.S.","1967-03-20","aa.51","cr.infil.",0,1]
[null,40,"0039/A","2018-11-12","P.C.A.","1969-02-24","aa.49","lob.infil.",1,2]
[null,41,"0040/A","2018-11-12","B.B.","1965-07-30","aa.53","cr.infil.",3,0]
[null,42,"0041/A","2018-11-19","M.M.","1974-05-09","aa.44","cr.infil.",3,2]
[null,43,"0042/A","2018-11-26","M.A.","1976-08-27","aa.42","cr.infil.",3,1]
[null,44,"0043/A","2018-11-26","P.G.","1967-06-02","aa.51","cr.infil.",1]
[null,45,"0044/A","2018-11-28","M.A.","1950-05-07","aa.68","cr.infil.",6,0]
[null,46,"0045/A","2018-12-04","P.R.","1953-03-15","aa.65","lob.infil.",0,0]
[null,47,"0046/A","2018-12-04","T.T.","1967-09-17","aa.51","cr.infil.",0]
[null,48,"0049/A","2019-01-07","P.T.","1968-07-18","aa.51","cr.infil.",7,2]
[null,49,"0050/A","2019-01-07","T.A.","1969-08-07","aa.50","cr.infil.",3,1]
[null,50,"0051/A","2019-01-21","M.R.","1969-09-28","aa.50","cr.infil.",1,0]

{"sheet":"Foglio2","index":1,"n_rows":74,"n_cols":12,"rows_kept":74,"flags":["formulas_cached_only"]}
[]
[{"$nulls":3},"             Aprile 2018-Febbraio 2019 dm Ø 17,25 mm (53 paz)",{"$nulls":7},914.5]
[{"$nulls":5}," Ø aa.  54,49 (57 paz)",{"$nulls":5},3150]
[" "]
["N°","Code","Istol.","Grado ist.","ER","PgR","Ki67","Eher2","In.v.","interv.","LS","pTNM"]
[1,"0000/A","sano"]
[2,"0021/A","sano"]
[3,"0035/A","sano"]
[]
[4,"0009/A","in situ","int.",98,60,{"$nulls":3},"mast.",null,"pT1"]
[5,"0015/A","in situ","alto",95,90,{"$nulls":3},"quad.",null,"pT1"]
[6,"0031/A","in situ","bas.",98,70,{"$nulls":3},"quad.","neg.","pT1"]
[]
[7,"0000/A","cr.infil.",2,90,70,25,"neg.","si","quad.","mic.","pT1cN1mi(sn)"]
[8,"0024/A","cr.infil.",2,98,98,10,"neg.","si","mast","pos.","pT4N2"]
[9,"0025/A","cr.infil.",2,95,50,28,"neg.","no","quad","neg","pT2,pN0"]
[]
[11,"0001/A","cr.infil.",3,0,0,50,"neg.","si","avanzato","pos.","pT3N2M1"]
[12,"0002/A","cr.infil.",3,95,30,70,"neg.","si","avanzato","pos.","pT3N2M1"]
[]
[13,"0003/A","cr.infil.",2,90,50,15,"neg.","si","mast.","pos.","pT3 N2a"]
[14,"0004/A","cr.infil.",1,95,0,15,"neg.","no","quad.","neg.","pT1a,pN0"]
[15,"0005/A","cr.infil.",2,95,60,30,"neg.","no","quad.","neg.","pT1c,pN0"]
[16,"0006/A","cr.infil.",3,40,90,35,"neg.","si","mast.","pos.","pT2,pN1a "]
[17,"0007/A","cr.infil.",3,20,5,80,"neg.","si","mast.","pos.","ypT1ypN0"]
[18,"0008/A","cr.infil.",1,99,70,3,"neg.","si","quad.","neg.","pT1c N0"]
[19,"0010/A","cr.infil.",2,60,80,7,"neg.","no","quad.","neg.","pT2 N0"]
[20,"0011/A","cr.infil.",1,80,80,5,"neg.","no","quad.","neg.","pT1b N0(sn)"]
[21,"0012/A","cr.infil.",2,90,80,20,"neg.","no","quad.","neg.","pT1b N0(sn)"]
[22,"0013/A","cr.infil.",2,90,95,25,"neg.","no","mast.","neg.","pT1b,N0"]
[23,"0014/A","cr.infil.",3,95,20,35,"neg.","si","quad.","mic.","pT1cN1mi(sn)"]
[24,"0016/A","cr.infil.",1,95,95,14,"neg.","no","quad.","neg.","pT1b,N0"]
[25,"0017/A","cr.infil.",2,70,0,40,"neg.","no","quad.","neg.","pT2N0"]
[26,"0018/A","cr.infil.",2,0,0,15,"neg.","no","quad.","neg.","p T1b N0"]
[27,"0019/A","cr.infil.",1,95,95,5,"neg.","no","quad","neg.","pT1b N0(sn)"]
[28,"0020/A","cr.infil.",3,0,0,45,"pos.","si","mast.","pos.","pT1c,pN1a(sn) "]
[29,"0022/A","cr.infil.",1,100,100,2,"neg.","no","quad","neg","pT1b, N0"]
[30,"0023/A","lob.infil.",2,100,80,10,"pos.","si","mast","pos.","pT1b N3"]
[31,"0026/A","cr.infil.",1,100,0,2,"neg.","no","quad","neg","pT1b,N0"]
[32,"0028/A","cr.infil.",2,100,70,2,"neg.","no","quad.","pos.","pT1cN1a"]
[33,"0029/A","cr.infil.",2,95,90,18,"neg.","no","quad","neg","pT1 N0"]
[34,"0030/A","cr.infil.",2,60,95,15,"neg.","no","quad.","neg.","pT1b N0(sn)"]
[35,"0032/A","cr.infil.",2,70,0,3,"neg.","si","mast","pos.","ypT2 N1a"]
[36,"0033/A","cr.infil.",3,0,0,40,"neg.","si","mast","pos.","ypT2N0"]
[37,"0034/A","cr.infil.",2,90,10,3,"neg.","no","quad.","neg.","pT1b N0(sn)"]
[38,"0036/A","cr.infil.",3,0,0,35,"pos.","no","quad.","neg.","pT1a,pN0"]
[39,"0037/A","cr.infil.",2,0,0,18,"neg.","no","quad.","neg","T1c N0(sn)"]
[40,"0038/A","cr.infil.",1,90,60,4,"neg.","no","quad.","neg.","pT1c pN0(sn)"]
[41,"0039/A","lob.inf.",2,90,90,2,"neg.","no","quad.","neg.","pT1c N0"]
[42,"0040/A","cr.infil.",2,95,95,10,"neg.","no","quad.","neg.","pT1b N0"]
[43,"0041/A","cr.infil.",2,80,80,10,"neg.","si","quad.","pos.","pT3 N2a"]
[44,"0042/A","cr.infil.",1,90,95,2,"neg.","no","mast","neg.","pT2N0"]
[45,"0043/A","cr.infil.",3,10,0,35,"pos.","si","mast","pos.","pT2N1a"]
[46,"0044/A","cr.infil.",1,98,98,3,"neg.","no","quad","mic.","pT1bN0"]
[47,"0045/A","lob.infil.",2,60,60,3,"neg.","no","quad",null,"pT1cNx"]
[48,"0046/A","cr.infil.",2,98,98,25,"neg.","no","mast","pos.","pT2N3a"]
[49,"0049/A","cr.infil.",1,100,70,3,"neg.","no","quad","neg","pT1bN0"]
[50,"0050/A","lob.infil.",2,{"$nulls":7},"pT1bN0"]
[51,"0051/A","cr.infil.",1,70,0,5,"neg.","no","quad","neg","pT1cN0"]
[52,"0052/A","lob.infil.",2,95,95,35,"neg.","no","quad","pos","pT1c,pN1a "]
[53,"0053/A","cr.infil.",1,98,0,2,"neg.","no","quad","neg","pT1a,pN0"]
[54,"0054/A","cr.infil.",1,100,95,7,"neg.","no","mast.","neg","pT1bN0"]
[55,"0055/A","cr.infil.",2,90,90,25,"neg.","si","mast.","pos","pT1cN3a"]
[56,"0056/A","cr.infil.",1,98,70,8,"neg.","no","quad.","neg","pT1b,N0"]
[57,"0057/A","cr.infil.",3,0,0,35,"neg.","no","mast.","pos","pT1b,N1a"]
[58]
[59]
[60]
[61,null,57,"prelievi",null,"1°"]
[62,null,23,null,null,"2°"]
[]
[null,null,"80 prelievi"]
[]
[10,"0027/A","cr.infil.",{"$nulls":5},"si",null,"neg"]

{"sheet":"Foglio3","index":2,"n_rows":74,"n_cols":8,"rows_kept":74,"flags":["formulas_cached_only"]}
[]
[{"$nulls":4},"             Aprile 2018-Febbraio 2019 dm Ø 17,25 mm (53 paz)"]
[{"$nulls":3},"Ø aa.  54,49 (57 paz)"]
[" "]
["N°","Code","1°CTC ","2°CTC ","cf DNA","Type","ctfDNA","ctcDNA"]
[1,"0000/A",0]
[2,"0021/A",0,null,0.2898,null,"NRAS","CTNNB1, HRAS"]
[3,"0035/A",0]
[]
[4,"0009/A",3,3,0.2653,null,null,"PTPN11"]
[5,"0015/A",0,null,0.3992,null,"APC","n.v."]
[6,"0031/A",1]
[]
[7,"0000/A",{"$nulls":3},"LB",null,"SOLO cfDNA"]
[8,"0024/A",null,null,0.2422,"LA",null,"SOLO cfDNA"]
[9,"0025/A",null,null,0.2393,"LB",null,"SOLO cfDNA"]
[]
[11,"0001/A",1,"†",2.8314,"B","n.v.","CTNNB1"]
[12,"0002/A",4,"†",40.317,"LB",null,"CTNNB1,RET"]
[]
[13,"0003/A",1,1,0.0615295,"LA",null,"BRAF"]
[14,"0004/A",2,0,0.0986435,"LA",null,"ALK,TP53"]
[15,"0005/A",6,1,0.06332525,"LB",null,"n.v."]
[16,"0006/A",7,4,0.236815,"LB","n.v.","n.v."]
[17,"0007/A",1,0,1.0665875,"LB","n.v."]
[18,"0008/A",28,0,0.43960375,"LA","n.v.","IDH1"]
[19,"0010/A",3,null,0.114105125,"LA",null,"ALK"]
[20,"0011/A",1,null,0.49610125,"LA","TSC1","IDH1"]
[21,"0012/A",1,null,0.320715,"LA","n.v."]
[22,"0013/A",10,1,0.268235,"LB",null,"n.v."]
[23,"0014/A",7,0,0.15557,"LB",null,"n.v."]
[24,"0016/A",1,2,0.21823625,"LA",null,"n.v."]
[25,"0017/A",3,3,0.22926,"LB",null,"FBXW7 , TP53"]
[26,"0018/A",3,3,0.107948,"B",null,"n.v."]
[27,"0019/A",0,1,0.05067625,"LA",null,"n.v."]
[28,"0020/A",1,0,0.2136175,"Her",null,"n.v."]
[29,"0022/A",2,4,0.31538375,"LA","PIK3CA, ALK, KRAS","NRAS, ALK, CDKH2A, KRAS"]
[30,"0023/A",0,null,0.01098915,"LA"]
[31,"0026/A",3,2,0.37078125,"LA",null,"n.v."]
[32,"0028/A",1,null,null,"LA"]
[33,"0029/A",7,3,null,"LA",null,"KRAS"]
[34,"0030/A",0,4,null,"LA"]
[35,"0032/A",0,1,null,"LA"]
[36,"0033/A",1,0,null,"B"]
[37,"0034/A",1,null,null,"LA"]
[38,"0036/A",5,3,null,"Her",null,"n.v."]
[39,"0037/A",4,0,null,"B",null,"FBXW7, BRAF, TP53"]
[40,"0038/A",0,null,null,"LA"]
[41,"0039/A",1,null,null,"LA"]
[42,"0040/A",3,null,null,"LA"]
[43,"0041/A",3,null,null,"LA"]
[44,"0042/A",3,1,null,"LA"]
[45,"0043/A",1,null,null,"Herb"]
[46,"0044/A",6,0,null,"LA"]
[47,"0045/A",0,null,null,"LA"]
[48,"0046/A",0,null,null,"LB"]
[49,"0049/A",7,2,null,"LA"]
[50,"0050/A",3,null,null,"LA"]
[51,"0051/A",1,null,null,"LA"]
[52,"0052/A",0,null,null,"LB"]
[53,"0053/A",0,null,null,"LA"]
[54,"0054/A",2,null,null,"LA"]
[55,"0055/A",2,null,null,"LB"]
[56,"0056/A",3,null,null,"LA"]
[57,"0057/A",2,null,null,"B"]
[58]
[59]
[60]
[61]
[62]
[]
[]
[]
[10,"0027/A",null,null,0.9369,null,"DNMT3A, APC","SOLO cfDNA"]